Identifying and Measuring Depression in Older Cancer Patients
About the study
The purpose of this study is to develop an accurate and useful way of measuring older patients' moods and reactions to the combined issue of cancer treatment and aging. Also, the purpose of this study is to test a new self-report measure of depressive symptoms tailored to the needs of older adults with cancer. Findings from this research will help us develop improved methods of diagnosis and treatment.
Who can take part
You may be eligible to participate in the study if you meet the following criteria:
INCLUSION CRITERIA
Inclusion Criteria:
For Patients in Phases 1- 3:
- Current or previous cancer diagnosis and treatment (any site and any stage)
- All Phases 1,2,3- 70 years of age or older
- For Phase 1b only; 50 participants ages 50-69 will also be recruited
- For Phase 2 only: As per medical record or self report, history of Depression, Dysthymia, or Adjustment Disorder with Depressed Mood
For Phase 3 depressive subset: As per medical record or self report, a history of depressive symptoms such as
- Adjustment Disorder with depressed mood
- Adjustment Disorder with mixed depressed mood and anxiety
- Mood disorder (i.e., due to general medical condition, Not Otherwise Specified)
- Depressive Disorder (i.e., Major Depressive Disorder (MDD) single episode, MDD recurrent, Depressive disorder not otherwise specified, Dysthymia)
- In the judgment of the consenting professional able to communicate, comprehend, and complete questionnaires in English
EXCLUSION CRITERIA
Exclusion Criteria:
For Patients in Parts 1- 3:
- In the judgment of the consenting professional and/or as per medical record, severe psychopathology or cognitive impairment likely to interfere with the participation or completion of the protocol or ability to provide meaningful information.
- For Phase 1&2 only: Score of > 11 on the Blessed Orientation-Memory-Concentration Scale (BOMC)
- For Part 2 only: As per medical record or self report, a diagnosis of a Schizophrenia Spectrum Disorder, current substance use disorder, Bipolar Disorder or Schizotypal personality disorder. Schizophrenia Spectrum Disorders include Schizophrenia, Schizophreniform disorder, Schizoaffective disorder, Delusional disorder, Brief psychotic disorder, Attenuated Psychotic Disorder, and Adjustment Disorder (except for Adjustment Disorder with Depressed Mood).
Study Locations
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How to Apply
Contact the study center to learn if this study is a good match for you.
Study’s details
Contition
Older Cancer Patients
Age (in years)
70+
Participants needed
290
Est. Completion Date
Jun 30, 2024
Treatment type
Observational
Sponsor
Memorial Sloan Kettering Cancer Center
ClinicalTrials.gov identifier
NCT02174055
Study number
14-101
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